IORA

Intraosseous Regional Administration of
Antibiotics in TKA

Please feel free to download information on Intraosseous Regional Administration of Antibiotics in Total Knee Arthroplasty, the topic of Simon Young’s doctoral thesis. No work may be republished without the express permission of the authors and copyright holders.


Doctoral Thesis

Preventing Infection in Knee Arthroplasty

Intraosseous Regional Administration of Antibiotics in Total Knee Arthroplasty
Simon W Young


Published Papers

The AAHKS Clinical Research Award: Intraosseous Regional Prophylaxis Provides Higher Tissue Concentrations in High BMI Patients in Total Knee Arthroplasty: A Randomized Trial (1)

The Journal of Arthroplasty 2018 Jul;33(7S):S13-S18.
Chin SJ, Moore GA, Zhang M, Clarke HD, Spangehl MJ, Young SW

Use of Regional Administration of Prophylactic Antibiotics in Total Knee Arthroplasty

ANZ Journal of Surgery 2018 Sep;88(9):848-853.
Symonds T, Parkinson B, Hazratwala K, McEwen P, Wilkinson M, Grant A

The John N. Insall Award: Higher Tissue Concentrations of Vancomycin Achieved With Intraosseous Regional Prophylaxis in Revision TKA: A Randomized Controlled Trial

Clinical Orthopaedics and Related Research 2018 Jan;476(1):66-74
Young SW, Zhang M, Moore GA, Pitto RP, Clarke HD, Spangehl MJ

Regional Intraosseous Administration of Prophylactic Antibiotics is More Effective Than Systemic Administration in a Mouse Model of TKA

Clinical Orthopaedics and Related Research 2015 Nov;473(11):3573-84.
Young SW, Roberts T, Johnson S, Dalton JP, Coleman B, Wiles S.

The Mark Coventry Award: Higher Tissue Concentrations of Vancomycin With Low-dose Intraosseous Regional Versus Systemic Prophylaxis in TKA A Randomized Trial

Clinical Orthopaedics and Related Research 2014 Jan;472(1):57-65.
Young SW, Zhang M, Freeman JT, Mutu-Grigg J, Pavlou P, Moore GA 

Higher Cefazolin Concentrations with Intraosseous Regional Prophylaxis in TKA

Clinical Orthopaedics and Related Research 2013 Jan;471(1):244-9.
Young SW, Zhang M, Freeman JT, Vince KG, Coleman B


Scientific Exhibit

Intraosseous Regional Administration of Antibiotics in Total Knee Arthroplasty

Scientific Exhibit AAOS 2019, Las Vegas
Simon W. Young, Henry D. Clarke, Mark J. Spangehl


Video Presentations

Intraosseous Injection in Adult with Tourniquet inflated

Injection radio-opaque dye

Intraosseous Injection in Child

Injection radio-opaque dye

IORA Injection Technique 1

IORA Technique Video
Simon W Young

IORA Injection Technique 2

IORA Technique Video
Henry D Clarke

IORA Talk Orthopaedic Infection Prevention Conference Melbourne 2019

Intraosseous Regional Administration of Antibiotics in Total Knee Arthroplasty

Mark Coventry Award - Intraosseous Regional Administration of Vancomycin

Knee Society, Chicago 2013
Simon W Young